Choosing the method of crystallization to obtain optimal results
File(s)
Published version
Author(s)
Govada, Lata
Chayen, Naomi
Type
Journal Article
Abstract
Anyone who has ever attempted to crystallise a protein or other biological macromolecule has encountered at least one, if not all of the following scenarios: No crystals at all, tiny low quality crystals; phase separation; amorphous precipitate and the most frustrating; large, beautiful crystals that do not diffract at all. In this paper we review a number of simple ways to overcome such problems, which have worked well in our hands and in other laboratories. It brings together information that has been dispersed in various publications and lectures over the years and includes further information that has not been previously published.
Date Issued
2019-02-19
Date Acceptance
2019-02-16
Citation
Crystals, 2019, 9 (2)
ISSN
2073-4352
Publisher
MDPI AG
Journal / Book Title
Crystals
Volume
9
Issue
2
Copyright Statement
© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
License URL
Publication Status
Published
Article Number
106