Medikamentöse Therapie der Adipositas – Konkurrenz zur bariatrischen Chirurgie oder sinnvolle Ergänzung? [Pharmacotherapy of obesity-Competition to bariatric surgery or a meaningful supplement?]
File(s)
Accepted version
Author(s)
Type
Journal Article
Abstract
Obesity is a complex chronic disease and requires a long-term multimodal approach. The current treatment algorithm for treatment of obesity mainly consists of a stepwise approach, which starts with a lifestyle intervention followed by or combined with medication treatment, whereas bariatric surgery is often reserved for the last option. This article provides an overview of the currently available conservative medicinal treatment regimens and the currently approved medications as well as medications currently undergoing approval studies with respect to the efficacy and possible side effects. Special attention is paid to the importance of combination treatment of pharmacotherapy and surgery in the sense of a multimodal treatment. The data so far show that using a multimodal approach an improvement in the long-term weight loss and metabolic benefits can be achieved for the patients.
Date Issued
2023-03-14
Date Acceptance
2023-01-26
Citation
Die Chirurgie, 2023, 94 (6), pp.497-505
ISSN
2731-6971
Publisher
Springer
Start Page
497
End Page
505
Journal / Book Title
Die Chirurgie
Volume
94
Issue
6
Copyright Statement
© 2023, The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature. This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://link.springer.com/article/10.1007/s00104-023-01830-z
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/36918431
PII: 10.1007/s00104-023-01830-z
Subjects
Combined treatment
Efficacy
Long-term weight loss
Side effects
Treatment algorithm
Publication Status
Published
Coverage Spatial
Germany
Date Publish Online
2023-03-14