Posterolateral corner (PLC) structures of the knee joint comprise complex anatomical soft
tissues that support static and dynamic functional movements of the knee. Most previous
studies analyzed posterolateral stability in vitro under static loading conditions. This study
aimed to evaluate the contributions of the lateral (fibular) collateral ligament (LCL), popliteofibular ligament (PFL), and popliteus tendon (PT) to cruciate ligament forces under simulated dynamic loading conditions by using selective individual resection. We combined
medical imaging and motion capture of healthy subjects (four males and one female) to
develop subject-specific knee models that simulated the 12 degrees of freedom of tibiofemoral and patellofemoral joint behaviors. These computational models were validated by
comparing electromyographic (EMG) data with muscle activation data and were based on
previous experimental studies. A rigid multi-body dynamics simulation using a lower extremity musculoskeletal model was performed to incorporate intact and selective resection of ligaments, based on a novel force-dependent kinematics method, during gait (walking) and
squatting. Deficiency of the PLC structures resulted in increased loading on the posterior
cruciate ligament and anterior cruciate ligament. Among PLC structures, the PT is the most
influential on cruciate ligament forces under dynamic loading conditions.