Theoretical implications of a pre-erythrocytic Plasmodium vivax vaccine for preventing relapses
File(s)
Published version
Author(s)
White, MT
Amino, R
Mueller, I
Type
Journal Article
Abstract
Preventing malaria infection through vaccination requires preventing every sporozoite inoculated by mosquito bite: a major challenge
for Plasmodium falciparum. Plasmodium vivax sporozoites consist of tachysporozoites causing primary infection and bradysporozoites leading to relapses.We hypothesise that a candidate P. vivax vaccine with low efficacy against primary infection may substantially reduce transmission by preventing relapses.
for Plasmodium falciparum. Plasmodium vivax sporozoites consist of tachysporozoites causing primary infection and bradysporozoites leading to relapses.We hypothesise that a candidate P. vivax vaccine with low efficacy against primary infection may substantially reduce transmission by preventing relapses.
Date Issued
2017-01-08
Date Acceptance
2017-01-08
Citation
Trends in Parasitology, 2017, 33 (4), pp.260-263
ISSN
1471-5007
Publisher
Elsevier (Cell Press)
Start Page
260
End Page
263
Journal / Book Title
Trends in Parasitology
Volume
33
Issue
4
Copyright Statement
© 2017 The Authors. Published by Elsevier Ltd. This is an open access article under a Creative Commons Licence 4.0 (https://creativecommons.org/licenses/by/4.0/)
Sponsor
Medical Research Council (MRC)
Identifier
http://www.cell.com/trends/parasitology/fulltext/S1471-4922(16)30234-3
Grant Number
MR/L012170/1
Subjects
Mycology & Parasitology
06 Biological Sciences
07 Agricultural And Veterinary Sciences
11 Medical And Health Sciences
Publication Status
Published