Fission yeast obeys a linear size law under nutrient titration
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Author(s)
Bertaux, François
Kleijn, Istvan
Marguerat, Samuel
Shahrezaei, Vahid
Type
Journal Article
Abstract
Steady-state cell size and geometry depend on growth conditions. Here, we use an experimental setup based on continuous culture and single-cell imaging to study how cell volume, length, width and surface-to-volume ratio vary across a range of growth conditions including nitrogen and carbon titration, the choice of nitrogen source, and translation inhibition. Overall, we find cell geometry is not fully determined by growth rate and depends on the specific mode of growth rate modulation. However, under nitrogen and carbon titrations, we observe that the cell volume and the growth rate follow the same linear scaling.
Date Issued
2023-05-12
Date Acceptance
2023-04-24
Citation
microPublication Biology, 2023, 2023
ISSN
2578-9430
Publisher
Caltech Library
Journal / Book Title
microPublication Biology
Volume
2023
Copyright Statement
© 2023 by the authors. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
License URL
Publication Status
Published
Date Publish Online
2023-04-28