Multiple adversarial learning based angiography reconstruction for ultra-low-dose contrast medium CT.
File(s)JBHI-00936-2022.R1_Proof_hi copy.pdf (9.36 MB)
Accepted version
Author(s)
Type
Journal Article
Abstract
Iodinated contrast medium (ICM) dose reduction is beneficial for decreasing potential health risk to renal-insufficiency patients in CT scanning. Due to the lowintensity vessel in ultra-low-dose-ICM CT angiography, it cannot provide clinical diagnosis of vascular diseases. Angiography reconstruction for ultra-low-dose-ICM CT can enhance vascular intensity for directly vascular diseases diagnosis. However, the angiography reconstruction is challenging since patient individual differences and vascular disease diversity. In this paper, we propose a Multiple Adversarial Learning based Angiography Reconstruction (i.e., MALAR) framework to enhance vascular intensity. Specifically, a bilateral learning mechanism is developed for mapping a relationship between source and target domains rather than the image-to-image mapping. Then, a dual correlation constraint is introduced to characterize both distribution uniformity from across-domain features and sample inconsistency with domain simultaneously. Finally, an adaptive fusion module by combining multiscale information and long-range interactive dependency is explored to alleviate the interference of high-noise metal. Experiments are performed on CT sequences with different ICM doses. Quantitative results based on multiple metrics demonstrate the effectiveness of our MALAR on angiography reconstruction. Qualitative assessments by radiographers confirm the potential of our MALAR for the clinical diagnosis of vascular diseases. The code and model are available at https://github.com/HIC-SYSU/MALAR.
Date Issued
2023-01
Date Acceptance
2022-10-02
Citation
IEEE Journal of Biomedical and Health Informatics, 2023, 27 (1), pp.409-420
ISSN
2168-2194
Publisher
Institute of Electrical and Electronics Engineers
Start Page
409
End Page
420
Journal / Book Title
IEEE Journal of Biomedical and Health Informatics
Volume
27
Issue
1
Copyright Statement
Copyright © 2022 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/36219660
Publication Status
Published
Coverage Spatial
United States
Date Publish Online
2022-10-11