Hybrid 3D printed-paper microfluidics
File(s)
Published version
Author(s)
Zargaryan, Arthur
Farhoudi, Nathalie
Haworth, George
Ashby, Julian
Au, Sam H
Type
Journal Article
Abstract
3D printed and paper-based Microfluidics are promising formats for applications that require portable miniaturized fluid handling such as point-of-care testing. These formats deployed in isolation, however, have inherent limitations that hamper their capabilities and versatility. Here, we present the convergence of 3D printed and paper formats into hybrid devices that overcome many of these limitations, while capitalizing on their respective strengths. Hybrid channels were fabricated with no specialized equipment except a commercial 3D printer. Finger-operated reservoirs and valves capable of fully-reversible dispensation and actuation were designed for intuitive operation without equipment or training. Components were then integrated into a versatile multicomponent device capable of dynamic fluid pathing. These results are an early demonstration of how 3D printed and paper microfluidics can be hybridized into powerful and versatile lab-on-chip devices.
Date Issued
2020-10-27
Date Acceptance
2020-10-08
Citation
Scientific Reports, 2020, 10
ISSN
2045-2322
Publisher
Nature Publishing Group
Journal / Book Title
Scientific Reports
Volume
10
Copyright Statement
© The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
License URL
Sponsor
Wellcome Trust
Grant Number
212391/Z/18/Z
Publication Status
Published
Article Number
ARTN 18379