Buffer materials for nuclear waste disposal applications generally consist of blocks made of highly expansive compacted clay. However, high-density pellets of bentonite are being evaluated as an alternative buffer material for waste isolation. The material response of pellet-based buffers may be quite different from that of compacted buffers, because of the peculiar discontinuous porosity presented. An overview of the literature available on pellet-based buffers is presented and, in particular, two main topics are discussed: firstly, the characteristics of the fabric of the pellets that can be observed through techniques of micro-structural investigation, secondly, the most important behavioural features that can be seen during material testing. Additionally, the constitutive frameworks that have already been developed specifically for pellets are also reviewed. The overall objective of the paper is to highlight the differences between compacted and pellet-based bentonite buffers, in order to propose suitable assumptions to start developing a constitutive model for the latter.