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A complicated multisystem flare of systemic lupus erythematosus during pregnancy.
File(s)
Author(s)
Webster, P
Nelson-Piercy, C
Lightstone, L
Type
Journal Article
Abstract
We report a case of systemic lupus erythematosus (SLE) in a young woman who became pregnant amid a severe flare. She continued to have active disease in the face of aggressive treatments complicated by several side effects of immunosuppressive drugs including recurrent sepsis and gestational diabetes. Her fetus was at risk for congenital heart block during the second and third trimesters. Despite an extremely guarded prognosis, she delivered a healthy baby girl. This case highlights the complexities of SLE management during pregnancy. We discuss the therapeutic options available in pregnancy, and highlight the importance of cross-specialty multidisciplinary care in these women.
Date Issued
2017-02-08
Date Acceptance
2017-01-23
Citation
BMJ Case Reports, 2017, 2017
URI
DOI
ISSN
1757-790X
Publisher
BMJ Publishing Group
Journal / Book Title
BMJ Case Reports
Volume
2017
Copyright Statement
© 2017 BMJ Publishing Group. All rights reserved. For permission to reuse any of this content visit
http://group.bmj.com/group/rights-licensing/permissions. This article has been accepted for publication in BMJ Case Reports following peer review. The definitive copyedited, typeset version
Webster P, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2016-217546 is available online at: https://dx.doi.org/10.1136/bcr-2016-217546
Sponsor
Imperial College Healthcare NHS Trust- BRC Funding
Identifier
http://www.ncbi.nlm.nih.gov/pubmed/28179384
PII: bcr-2016-217546
Grant Number
RDA04 79560
Subjects
Adult
Diabetes, Gestational
Female
Humans
Immunosuppressive Agents
Lupus Erythematosus, Systemic
Pregnancy
Pregnancy Complications
Pregnancy Outcome
Publication Status
Published
Coverage Spatial
England