System size expansion using Feynman rules and diagrams
File(s)1409.1439v1.pdf (635.63 KB)
Accepted version
Author(s)
Thomas, Philipp
Fleck, Christian
Grima, Ramon
Popovic, Nikola
Type
Journal Article
Abstract
Few analytical methods exist for quantitative studies of large fluctuations in stochastic systems. In this article, we develop a simple diagrammatic approach to the chemical master equation that allows us to calculate multi-time correlation functions which are accurate to any desired order in van Kampenʼs system size expansion. Specifically, we present a set of Feynman rules from which this diagrammatic perturbation expansion can be constructed algorithmically. We then apply the methodology to derive in closed form the leading order corrections to the linear noise approximation of the intrinsic noise power spectrum for general biochemical reaction networks. Finally, we illustrate our results by describing noise-induced oscillations in the Brusselator reaction scheme which are not captured by the common linear noise approximation.
Date Issued
2014-11-14
Date Acceptance
2014-09-18
Citation
JOURNAL OF PHYSICS A-MATHEMATICAL AND THEORETICAL, 2014, 47 (45)
ISSN
1751-8113
Publisher
IOP PUBLISHING LTD
Journal / Book Title
JOURNAL OF PHYSICS A-MATHEMATICAL AND THEORETICAL
Volume
47
Issue
45
Copyright Statement
© 2014 IOP Publishing Ltd. This is an author-created, un-copyedited version of an article accepted for publication in
Journal of Physics A: Mathematical and Theoretical. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The definitive publisher authenticated version is available online at https://dx.doi.org/10.1088/1751-8113/47/45/455007
Journal of Physics A: Mathematical and Theoretical. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The definitive publisher authenticated version is available online at https://dx.doi.org/10.1088/1751-8113/47/45/455007
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344628200008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Physical Sciences
Physics, Multidisciplinary
Physics, Mathematical
Physics
master equations
noise
chemical reactions
LINEAR NOISE APPROXIMATION
STOCHASTIC GENE-EXPRESSION
CHEMICAL MASTER EQUATION
BIRTH-DEATH PROCESSES
POISSON REPRESENTATION
FLUCTUATIONS
OSCILLATIONS
NETWORKS
Publication Status
Published
Article Number
UNSP 455007
Date Publish Online
2014-10-29