For a population of cells to continuously reproduce, they must undergo two distinct fundamental processes; they need to grow, thus increasing their volume and their biomass, and they need to undergo cell division cycles, thus replicating their genetic information and propagating it to two daughter cells. Growth is a continuous process whilst the cell cycle consists of discrete events that take place in an ordered manner. How the production of biomass is coordinated through growth and through the discrete events of the cell cycles is not fully understood. DNA, the template for all RNA molecules and ultimately proteins, is replicated once per cell cycle. How cell size, the amount of DNA, and cell cycle changes affect the global production of RNA molecules and proteins remains unclear. In this work I develop single-cell assays to measure the level of global transcription and translation in unperturbed populations of yeast cells whilst monitoring the cell cycle stage of each cell and precisely measuring its size. I show that global transcription scales with both size and the amount of DNA, thus supporting the idea that the level of transcription of a cell is the result of a dynamic equilibrium between the number of RNA polymerases associating and disassociating from DNA. In addition, global translation scales with size, but also increases at a discrete stage of the cell cycle in late S-phase or early G2. Finally, the global translation assay reveals an unexpected single-cell temporal variability in the metabolic pathway responsible for the uptake and incorporation into peptides of an exogenous amino acid, and that this variability is modulated by proteins involved in the cell cycle and in the TOR pathway.