Epilepsy seizure prediction on EEG using common spatial pattern and convolutional neural network
Author(s)
Zhang, Yuan
Guo, Yao
Yang, Po
Chen, Wei
Lo, Benny
Type
Journal Article
Abstract
Epilepsy seizure prediction paves the way of timely warning for patients to take more active and effective intervention measures. Compared to seizure detection that only identifies the inter-ictal state and the ictal state, far fewer researches have been conducted on seizure prediction because the high similarity makes it challenging to distinguish between the pre-ictal state and the inter-ictal state. In this paper, a novel solution on seizure prediction is proposed using common spatial pattern (CSP) and convolutional neural network (CNN). Firstly, artificial preictal EEG signals based on the original ones are generated by combining the segmented pre-ictal signals to solve the trial imbalance problem between the two states. Secondly, a feature extractor employing wavelet packet decomposition and CSP is designed to extract the distinguishing features in both the time domain and the frequency domain. It can improve overall accuracy while reducing the training time. Finally, a shallow CNN is applied to discriminate between the pre-ictal state and the inter-ictal state. Our proposed solution is evaluated on 23 patients' data from Boston Children's Hospital-MIT scalp EEG dataset by employing a leave-one-out cross-validation, and it achieves a sensitivity of 92.2% and false prediction rate of 0.12/h. Experimental result demonstrates that the proposed approach outperforms most state-of-the-art methods.
Date Issued
2020-02-01
Date Acceptance
2019-07-29
Citation
IEEE Journal of Biomedical and Health Informatics, 2020, 24 (2), pp.465-474
ISSN
2168-2194
Publisher
Institute of Electrical and Electronics Engineers
Start Page
465
End Page
474
Journal / Book Title
IEEE Journal of Biomedical and Health Informatics
Volume
24
Issue
2
Copyright Statement
© 2020 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000516606600015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Technology
Life Sciences & Biomedicine
Computer Science, Information Systems
Computer Science, Interdisciplinary Applications
Mathematical & Computational Biology
Medical Informatics
Computer Science
Seizure prediction
EEG
common spatial patterns
convolutional neural network
SPECTRAL POWER
TIME
CLASSIFICATION
Publication Status
Published
Date Publish Online
2019-08-05