Perspectives in allergen immunotherapy: 2017 and beyond
File(s)
Author(s)
Type
Journal Article
Abstract
The Future of the Allergists and Specific Immunotherapy (FASIT) workshop provides a regular platform for global experts from academia, allergy clinics, regulatory authorities and industry to review developments in the field of allergen immunotherapy (AIT). The most recent meeting, held in February 2017, had two main themes: advances in AIT and hot topics in AIT from the regulatory point of view. The first theme covered opportunities for personalized AIT, advances in adjuvants and delivery systems, and the development of new molecules and future vaccines for AIT. Key topics in the second part of the meeting were the effects of the enactment of European Directive 2001/83 on the availability of allergens for therapy and diagnosis across the EU, the challenges of conducting Phase 3 studies in the field, the future role of allergen exposure chambers in AIT studies and specific considerations in performing AIT studies in the paediatric population. Finally, the group highlighted the forthcoming EAACI guidelines and their particular importance for the standardization of practice in the treatment of allergies. This review presents a comprehensive insight into those panel discussions and highlights unmet needs and also possible solutions to them for the future.
Date Issued
2018-01-03
Date Acceptance
2017-11-08
Citation
Allergy, 2018, 73 (S104), pp.5-23
ISSN
0105-4538
Publisher
Wiley
Start Page
5
End Page
23
Journal / Book Title
Allergy
Volume
73
Issue
S104
Copyright Statement
© 2018 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd. This is the peer reviewed version of the following article: [insert full citation], which has been published in final form at https://dx.doi.org/10.1111/all.13355
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000419230000001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Life Sciences & Biomedicine
Allergy
Immunology
Allergen immunotherapy
biomarkers
invivo diagnostics
legislation
precision medicine
ENVIRONMENTAL EXPOSURE CHAMBER
EAACI POSITION PAPER
HISTAMINE-SECRETING MICROBES
DIAGNOSTIC-TEST ALLERGENS
GRASS-POLLEN ALLERGY
CLINICAL VALIDATION
CHALLENGE CHAMBER
INTERNATIONAL CONSENSUS
CHRONIC RHINOSINUSITIS
EUROPEAN LEGISLATION
Publication Status
Published
Date Publish Online
2017-11-24