The association between passive and active tobacco smoke exposure and child weight status among Spanish children.
File(s)Robinson ETS postnatal growth mainR1 clean.docx (104.55 KB)
Accepted version
Author(s)
Type
Journal Article
Abstract
OBJECTIVE: To assess the impact of passive and active tobacco smoke exposure, both pre- and postnatally, on child body mass index (BMI) and overweight. METHODS: Pregnant women were enrolled into the Spanish INMA prospective birth cohort during 1997 to 2008. Tobacco smoke exposure was assessed by questionnaire and corroborated by pre- and postnatal cotinine measurements. Children were followed up until 4 years in newer subcohorts (N = 1866) and until 14 years in one older subcohort (N = 427). Child age- and sex-specific BMI Z-scores were calculated, and generalized estimating equations were used to model their relationship with repeated measures of tobacco smoke exposure. RESULTS: Associations between prenatal passive exposure to tobacco smoke (adjusted beta = 0.15, 95% CI: 0.05-0.25) and active maternal smoking (adjusted beta = 0.20, 95% CI: 0.08-0.33) and child zBMI up to 4 years were observed. Stronger associations were observed in the older subcohort between both prenatal and child passive smoke exposure and zBMI up to 14 years. CONCLUSIONS: Evidence for an effect of both passive and maternal active smoking on child postnatal growth has been provided. Although residual confounding cannot be completely ruled out, associations were robust to adjustment for a range of lifestyle factors.
Date Issued
2016-07-01
Date Acceptance
2016-04-25
Citation
Obesity, 2016, 24 (8), pp.1767-1777
ISSN
1930-7381
Publisher
Wiley
Start Page
1767
End Page
1777
Journal / Book Title
Obesity
Volume
24
Issue
8
Copyright Statement
© 2016 The Obesity Society. This is the accepted version of the following article: Robinson, O. , Martínez, D. , Aurrekoetxea, J. J., Estarlich, M. , Somoano, A. F., Íñiguez, C. , Santa‐Marina, L. , Tardón, A. , Torrent, M. , Sunyer, J. , Valvi, D. and Vrijheid, M. (2016), The association between passive and active tobacco smoke exposure and child weight status among Spanish children. Obesity, 24: 1767-1777, which has been published in final form at https://dx.doi.org/10.1002/oby.21558
Subjects
Adult
Body Mass Index
Body Weight
Child
Female
Health Behavior
Hispanic Americans
Humans
Male
Overweight
Pediatric Obesity
Pregnancy
Prenatal Exposure Delayed Effects
Prospective Studies
Smoking
Surveys and Questionnaires
Tobacco Smoke Pollution
MD Multidisciplinary
Endocrinology & Metabolism
Notes
1930-739x Robinson, Oliver Martinez, David Aurrekoetxea, Juan J Estarlich, Marisa Somoano, Ana Fernandez Iniguez, Carmen Santa-Marina, Loreto Tardon, Adonina Torrent, Maties Sunyer, Jordi Valvi, Damaskini Vrijheid, Martine Journal Article United States Obesity (Silver Spring). 2016 Aug;24(8):1767-77. doi: 10.1002/oby.21558. Epub 2016 Jul 1. OBJECTIVE: To assess the impact of passive and active tobacco smoke exposure, both pre- and postnatally, on child body mass index (BMI) and overweight. METHODS: Pregnant women were enrolled into the Spanish INMA prospective birth cohort during 1997 to 2008. Tobacco smoke exposure was assessed by questionnaire and corroborated by pre- and postnatal cotinine measurements. Children were followed up until 4 years in newer subcohorts (N = 1866) and until 14 years in one older subcohort (N = 427). Child age- and sex-specific BMI Z-scores were calculated, and generalized estimating equations were used to model their relationship with repeated measures of tobacco smoke exposure. RESULTS: Associations between prenatal passive exposure to tobacco smoke (adjusted beta = 0.15, 95% CI: 0.05-0.25) and active maternal smoking (adjusted beta = 0.20, 95% CI: 0.08-0.33) and child zBMI up to 4 years were observed. Stronger associations were observed in the older subcohort between both prenatal and child passive smoke exposure and zBMI up to 14 years. CONCLUSIONS: Evidence for an effect of both passive and maternal active smoking on child postnatal growth has been provided. Although residual confounding cannot be completely ruled out, associations were robust to adjustment for a range of lifestyle factors.
Publication Status
Published