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“Design principles of a membrane-spanning ubiquitin ligase”
OA Location
Author(s)
Williams, Carys
Nocka, Laura M
Hedger, George
Parashara, Pragya
Pardon, Els
Type
preprint
Date Issued
2025-09-16
Date Acceptance
2025-09-16
Citation
bioRxiv, 2025
URI
URL
DOI
Journal / Book Title
bioRxiv
Copyright Statement
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
License URL
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/41000701
PII: 2025.09.11.675358
Subjects
Carpenter syndrome
E3 ligase
birth defects
cryo-EM structure
molecular dynamics simulations
morphogens
signaling
transmembrane receptor
ubiquitylation
Publication Status
Published
Coverage Spatial
United States