Characterisation of Bioglass based foams developed via replication of natural marine sponges
Author(s)
Type
Journal Article
Abstract
A comparative characterisation of Bioglass based scaffolds for bone tissue engineering applications developed via a replication technique of natural marine sponges as sacrificial template is presented, focusing on their architecture and mechanical properties. The use of these sponges presents several advantages, including the possibility of attaining higher mechanical properties than those scaffolds made by foam replica method (up to 4 MPa) due to a decrease in porosity (68-76%) without affecting the pore interconnectivity (higher than 99%). The obtained pore structure possesses not only pores with a diameter in the range 150-500 mm, necessary to induce bone ingrowth, but also pores in the range of 0-200 mm, which are requested for complete integration of the scaffold and for neovascularisation. In this way, it is possible to combine the main properties that a three-dimensional scaffold should have for bone regeneration: interconnected and high porosity, adequate mechanical properties and bioactivity.
Date Issued
2015-07-02
Date Acceptance
2015-05-27
Citation
Advances in Applied Ceramics, 2015, 114 (Suppl 1), pp.S56-S62
ISSN
1743-6753
Publisher
Taylor & Francis
Start Page
S56
End Page
S62
Journal / Book Title
Advances in Applied Ceramics
Volume
114
Issue
Suppl 1
Copyright Statement
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
License URL
Subjects
Materials
0912 Materials Engineering
Publication Status
Published