A maximum entropy deep reinforcement learning neural tracker
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Accepted version
Author(s)
Balaram, Shafa
Arulkumaran, Kai
Dai, Tianhong
Bharath, Anil Anthony
Type
Conference Paper
Abstract
Tracking of anatomical structures has multiple applications in the field of biomedical imaging, including screening, diagnosing and monitoring the evolution of pathologies. Semi-automated tracking of elongated structures has been previously formulated as a problem suitable for deep reinforcement learning (DRL), but it remains a challenge. We introduce a maximum entropy continuous-action DRL neural tracker capable of training from scratch in a complex environment in the presence of high noise levels, Gaussian blurring and detractors. The trained model is evaluated on two-photon microscopy images of mouse cortex. At the expense of slightly worse robustness compared to a previously applied DRL tracker, we reach significantly higher accuracy, approaching the performance of the standard hand-engineered algorithm used for neuron tracing. The higher sample efficiency of our maximum entropy DRL tracker indicates its potential of being applied directly to small biomedical datasets.
Editor(s)
Suk, HI
Liu, M
Yan, P
Lian, C
Date Issued
2019-10-10
Date Acceptance
2019-10-01
Citation
MACHINE LEARNING IN MEDICAL IMAGING (MLMI 2019), 2019, 11861, pp.400-408
ISBN
978-3-030-32691-3
ISSN
0302-9743
Publisher
SPRINGER INTERNATIONAL PUBLISHING AG
Start Page
400
End Page
408
Journal / Book Title
MACHINE LEARNING IN MEDICAL IMAGING (MLMI 2019)
Volume
11861
Copyright Statement
© Springer Nature Switzerland AG 2019. The final publication is available at Springer via https://doi.org/10.1007/978-3-030-32692-0_46
Sponsor
Samsung Electronics Co. Ltd
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000548437800046&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Grant Number
BMPF_P70273
Source
10th International Workshop on Machine Learning in Medical Imaging (MLMI) / 22nd International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI)
Subjects
Science & Technology
Technology
Life Sciences & Biomedicine
Computer Science, Artificial Intelligence
Computer Science, Interdisciplinary Applications
Radiology, Nuclear Medicine & Medical Imaging
Computer Science
Tracking
Tracing
Neuron
Axon
Reinforcement learning
Maximum entropy
SEGMENTATION
IMAGES
Publication Status
Published
Start Date
2019-10-13
Finish Date
2019-10-17
Coverage Spatial
Shenzhen, PEOPLES R CHINA
Date Publish Online
2019-10-10