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TLR4 activation induces IL-1 beta release via an IPAF dependent but caspase 1/11/8 independent pathway in the lung
File(s)
Author(s)
Eltom, S
Belvisi, MG
Yew-Booth, L
Dekkak, B
Maher, SA
Type
Journal Article
Date Issued
2014-08-02
URI
DOI
ISSN
1465-993X
Publisher
BIOMED CENTRAL LTD
Journal / Book Title
RESPIRATORY RESEARCH
Volume
15
Copyright Statement
© 2014 Eltom et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative
Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and
reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain
Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article,
unless otherwise stated.
Sponsor
Medical Research Council (MRC)
Medical Research Council (MRC)
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339999900001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Grant Number
G1000758
G1000758
Subjects
Science & Technology
Life Sciences & Biomedicine
Respiratory System
RESPIRATORY SYSTEM
TLR4
IPAF
ASC
IL-1 release
INTERLEUKIN-1-ALPHA PRECURSOR
IL-1-BETA-CONVERTING ENZYME
MATRIX METALLOPROTEINASES
MONOCYTIC CELLS
ACTIVE IL-1
HUMAN BLOOD
SECRETION
RECEPTOR
ATP
INFLAMMASOME
Administration, Inhalation
Aerosols
Animals
Apoptosis Regulatory Proteins
Bronchoalveolar Lavage Fluid
Calcium-Binding Proteins
Caspase 1
Caspase 8
Caspases
Endotoxins
Inflammation Mediators
Interleukin-18
Interleukin-1beta
Lung
Male
Mice, Inbred C57BL
Mice, Knockout
RNA, Messenger
Signal Transduction
Time Factors
Toll-Like Receptor 4
1102 Cardiovascular Medicine And Haematology
1103 Clinical Sciences
Publication Status
Published
Article Number
ARTN 87