Cognitive health in persons with human immunodeficiency virus: the impact of early treatment, comorbidities, and aging
Author(s)
Type
Journal Article
Abstract
With the advent of virally suppressive antiretroviral therapy (ART), life expectancy for persons with human immunodeficiency virus (HIV) with access to ART now approaches that of the general population. As persons with HIV age, noninfectious comorbidities occur more frequently compared with persons without HIV. Such comorbidities are likely to affect cognitive health, which may also be affected by lifestyle factors that may differ in persons with HIV.
At the National Institutes of Health–supported meeting on Biotypes of Central Nervous System (CNS) Complications in persons with HIV, a session was devoted to early HIV treatment, noninfectious comorbidities, and aging as each pertains to cognitive health. Areas of consideration included acute and early HIV infection (presentation by Phillip Chan), drugs of abuse (Scott Letendre), stroke and cerebrovascular disease (Felicia Chow), mental health (John Joska), and aging (Julian Falutz).
These presentations were followed by a discussion session led by Woody Lin, Jose A. Muñoz-Moreno, Paola Cinque, and Jeff Taylor. Alan Winston and Bruce Brew chaired the meeting with Jasmini Alagaratnam and Htein Linn Aung acting as rapporteurs.
Here we present the main topics covered in the presentations, and the associated discussions highlighting knowledge gaps and future directions.
At the National Institutes of Health–supported meeting on Biotypes of Central Nervous System (CNS) Complications in persons with HIV, a session was devoted to early HIV treatment, noninfectious comorbidities, and aging as each pertains to cognitive health. Areas of consideration included acute and early HIV infection (presentation by Phillip Chan), drugs of abuse (Scott Letendre), stroke and cerebrovascular disease (Felicia Chow), mental health (John Joska), and aging (Julian Falutz).
These presentations were followed by a discussion session led by Woody Lin, Jose A. Muñoz-Moreno, Paola Cinque, and Jeff Taylor. Alan Winston and Bruce Brew chaired the meeting with Jasmini Alagaratnam and Htein Linn Aung acting as rapporteurs.
Here we present the main topics covered in the presentations, and the associated discussions highlighting knowledge gaps and future directions.
Date Issued
2023-03-17
Date Acceptance
2022-09-15
Citation
Journal of Infectious Diseases, 2023, 227 (Supplement_1), pp.S38-S47
ISSN
0022-1899
Publisher
Oxford University Press
Start Page
S38
End Page
S47
Journal / Book Title
Journal of Infectious Diseases
Volume
227
Issue
Supplement_1
Copyright Statement
© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases
Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/),
which permits non-commercial reproduction and distribution of the work, in any medium, pro-
vided the original work is not altered or transformed in any way, and that the work is properly
cited. For commercial re-use, please contact journals.permissions@oup.com
https://doi.org/10.1093/infdis/jiac388
Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/),
which permits non-commercial reproduction and distribution of the work, in any medium, pro-
vided the original work is not altered or transformed in any way, and that the work is properly
cited. For commercial re-use, please contact journals.permissions@oup.com
https://doi.org/10.1093/infdis/jiac388
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/36930639
PII: 7079926
Subjects
Aging
Cognition
Comorbidity
HIV
HIV Infections
Humans
Publication Status
Published
Coverage Spatial
United States
Date Publish Online
2023-03-17