Modelling for Taenia solium control strategies beyond 2020
File(s)Dixon et al. Bull WHO_BLT.19.238485.pdf (885.15 KB)
Accepted version
Author(s)
Type
Journal Article
Abstract
The cestode Taenia solium is responsible for a considerable cross-sectoral health and economic burden due to human neurocysticercosis and porcine cysticercosis. The 2012 World Health Organization (WHO) roadmap for neglected tropical diseases called for the development of a validated strategy for control of T. solium; however, such a strategy is not yet available. In 2019, WHO launched a global consultation aimed at refining the post-2020 targets for control of T. solium for a new roadmap for neglected tropical diseases. In response, two groups working on taeniasis and cysticercosis mathematical models (cystiSim and EPICYST models), together with a range of other stakeholders organized a workshop to provide technical input to the WHO consultation and develop a research plan to support efforts to achieve the post-2020 targets. The workshop led to the formation of a collaboration, CystiTeam, which aims to tackle the population biology, transmission dynamics, epidemiology and control of T. solium through mathematical modelling approaches. In this paper, we outline developments in T. solium control and in particular the use of modelling to help achieve post-2020 targets for control of T. solium. We discuss the steps involved in improving confidence in the predictive capacities of existing mathematical and computational models on T. soliumtransmission, including model comparison, refinement, calibration and validation. Expanding the CystiTeam partnership to other research groups and stakeholders, particularly those operating in different geographical and endemic areas, will enhance the prospects of improving the applicability of T. solium transmission models to inform taeniasis and cysticercosis control strategies.
Date Issued
2020-01-27
Date Acceptance
2019-12-28
Citation
Bulletin of the World Health Organization, 2020, 98, pp.198-205
ISSN
0042-9686
Publisher
World Health Organization
Start Page
198
End Page
205
Journal / Book Title
Bulletin of the World Health Organization
Volume
98
Copyright Statement
This paper is subject to copyright. This accepted version is available under the Creative Commons Attribution 3.0 IGO licence (CC BY 3.0 IG0).
Identifier
https://www.who.int/bulletin/volumes/98/3/19-238485.pdf
Subjects
Science & Technology
Life Sciences & Biomedicine
Public, Environmental & Occupational Health
TRANSMISSION
Animals
Cysticercosis
Humans
Models, Theoretical
Neurocysticercosis
Swine
Taenia solium
Taeniasis
World Health Organization
Zoonoses
Animals
Swine
Humans
Taenia solium
Zoonoses
Neurocysticercosis
Taeniasis
Cysticercosis
Models, Theoretical
World Health Organization
11 Medical and Health Sciences
Tropical Medicine
Publication Status
Published online
Date Publish Online
2020-01-27