The Impact of poor glycaemic control on the prevalence of erectile dysfunction in men with type 2 Diabetes Mellitus: A Systematic Review.
File(s)
Author(s)
Binmoammar, T
Hassounah, SOA
Rawaf, S
Majeed, A
Alsaad, S
Type
Journal Article
Abstract
BACKGROUND: The importance of poor glycaemic control as an indicator of
reduced erectile function in diabetic men is still unclear. Several studies
have demonstrated a significant correlation, however, some studies show
only a borderline or no correlation between the two. In our review, we aim
to clearly determine the impact of poor glycaemic control on the
prevalence of erectile dysfunction (ED) in men with type 2 diabetes
mellitus (DM), as well as the impact of other possible risk factors on the
prevalence of ED.
METHODS: The databases Embase, Medline, Global health and PsychINFO
were systematically searched for relevant research to identify the studies
that evaluated the association between poor glycaemic control and the
prevalence of ED in men with type 2 DM.
RESULTS: Five cross sectional studies involving 3299 patients were
included. The findings pointed to a positive association between ED and
glycaemic control. Three studies showed a significant positive association,
while one study showed only a weak correlation and one study showed
borderline significance. Patients’ age, DM duration, peripheral neuropathy
and body mass index had positive association with ED. However, smoking
and hypertension was not associated with ED in most included studies.
Physical activity had a protective effect against ED.
CONCLUSION: We may conclude that the risk of ED is higher in type 2
diabetic men with poor glycaemic control than those with good control.
reduced erectile function in diabetic men is still unclear. Several studies
have demonstrated a significant correlation, however, some studies show
only a borderline or no correlation between the two. In our review, we aim
to clearly determine the impact of poor glycaemic control on the
prevalence of erectile dysfunction (ED) in men with type 2 diabetes
mellitus (DM), as well as the impact of other possible risk factors on the
prevalence of ED.
METHODS: The databases Embase, Medline, Global health and PsychINFO
were systematically searched for relevant research to identify the studies
that evaluated the association between poor glycaemic control and the
prevalence of ED in men with type 2 DM.
RESULTS: Five cross sectional studies involving 3299 patients were
included. The findings pointed to a positive association between ED and
glycaemic control. Three studies showed a significant positive association,
while one study showed only a weak correlation and one study showed
borderline significance. Patients’ age, DM duration, peripheral neuropathy
and body mass index had positive association with ED. However, smoking
and hypertension was not associated with ED in most included studies.
Physical activity had a protective effect against ED.
CONCLUSION: We may conclude that the risk of ED is higher in type 2
diabetic men with poor glycaemic control than those with good control.
Date Issued
2016-03-01
Date Acceptance
2015-11-13
Citation
JRSM open, 2016, 7 (3)
ISSN
2054-2704
Publisher
Sage
Journal / Book Title
JRSM open
Volume
7
Issue
3
License URL
Sponsor
Imperial College Trust
Grant Number
N/A
Publication Status
Published