Development and validation of a neonatal physical maturity score for low- and middle- income countries
File(s)
Published version
Author(s)
Type
Journal Article
Abstract
Currently available gestational age scoring systems are complex and inaccurate for wider use in low and middle-income countries(LMIC), particularly in infants with neonatal encephalopathy. Here we developed a scoring system based on physical characteristics for identifying late preterm infants from term infants. In the first phase, we examined the accuracy of 10 objective physical characteristics in a prospective cohort of 1006 babies recruited from three hospitals in South India. A weighted scoring system and a photo card were then developed based on the six best performing characteristics, which was validated in another prospective cohort of 1004 babies. The final score had a sensitivity of 66.0%, (95% Confidence intervals (CI), 58.4%-73.8%), specificity of 80.0%, (95% CI, 77.2%-82.7%) and a negative predictive value of 93.0%, (95%CI, 90.5%-94.5%). This scoring system may have wider applications in low and middle-income countries, particularly in community settings and in infants with neonatal encephalopathy.
Date Issued
2024
Date Acceptance
2022-07-06
Citation
American Journal of Perinatology: neonatal and maternal-fetal medicine, 2024, 41 (S 01), pp.e514-519
ISSN
0735-1631
Publisher
Thieme Gruppe
Start Page
e514
End Page
519
Journal / Book Title
American Journal of Perinatology: neonatal and maternal-fetal medicine
Volume
41
Issue
S 01
Copyright Statement
© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/35858649
Publication Status
Published
Coverage Spatial
United States
Date Publish Online
2022-09-12