Novel Balloon Surface Scanning Device for Intraoperative Breast Endomicroscopy
File(s)Zuo 2015 Novel Balloon Surface Scanning.pdf (1.09 MB)
Accepted version
Author(s)
Zuo, S
Hughes, M
Yang, GZ
Type
Journal Article
Abstract
Recent advances in fluorescence confocal endomicroscopy have allowed real-time identification of residual tumour cells on the walls of the cavity left by breast conserving surgery. However, it is difficult to systematically survey the surgical site because of the small imaging field-of-view of these probes, compounded by tissue deformation and inconsistent probe-tissue contact when operated manually. Therefore, a new robotized scanning device is required for controlled, large area scanning and mosaicing. This paper presents a robotic scanning probe with an inflatable balloon, providing stable cavity scanning over undulating surfaces. It has a compact design, with an outer diameter of 4 mm and a working channel of 2.2 mm, suitable for a leached flexible fibre bundle endomicroscope probe. With the probe inserted, the tip positioning accuracy measured to be 0.26 mm for bending and 0.17 mm for rotational motions. Large area scanning was achieved (25-35 mm(2)) and the experimental results demonstrate the potential clinical value of the device for intraoperative cavity tumour margin evaluation.
Date Issued
2015-10-27
Date Acceptance
2015-10-22
Citation
Annals of Biomedical Engineering, 2015, 44 (7), pp.2313-2326
ISSN
1573-9686
Publisher
Springer Verlag
Start Page
2313
End Page
2326
Journal / Book Title
Annals of Biomedical Engineering
Volume
44
Issue
7
Copyright Statement
© Springer-Verlag 2015. The final publication is available at Springer via http://dx.doi.org/10.1007/s10439-015-1493-2
Sponsor
Engineering & Physical Science Research Council (EPSRC)
Identifier
PII: 10.1007/s10439-015-1493-2
Grant Number
EP/I027769/1
Subjects
Breast conserving surgery
Confocal endomicroscopy
Image mosaicing
Mechanical design
Surgical robot
Biomedical Engineering
11 Medical And Health Sciences
09 Engineering
Publication Status
Published