Sodium and potassium content of a 24h urinary collection: A comparison between a field- and laboratory-based analyzer
File(s)Sodium & potassium content_20170711.pdf (374.14 KB)
Accepted version
Author(s)
Type
Journal Article
Abstract
Objectives:
Measurement of mean population sodium and potassium intake typically
using laboratory -based assays which can add significant logistical burden and costs. A valid field-based measurement method would be a significant advance. In this study, we used 166 24 -hour urine collection samples to compare estimates of sodium, potassium content and sodium/potassium ratio based upon assays done using the field-
based Horiba twin meter versus a laboratory-based method.
Design:
Aliquots of urine were assayed for sodium and potassium using the ion-selective electrode method with the field-based Horiba twin meter and the laboratory-based method. The performance of the Horiba twin meter was determined by comparing field-based estimates of mean
sodium and potassium against those obtained using the laboratory-
based methods.
Setting:
24-hour urine samples were collected as part of an ongoing study being done in rural China.
Subjects:
There were 166 subjects complete 24-hour urine samples available for estimating 24-hour urinary sodium and potassium excretion.
Results:
Mean sodium and potassium excretion were estimated as 170.4 mol/day and 37.4 mmol/day using the meter-based assays and 193.4 mmol/day and 43.8 mmol/day using the laboratory-based assays. There was excellent relative reliability for both sodium (ICC=0.986) and potassium (ICC=0.986). Bland-Altman plots showed moderate-to-good
agreement between two methods.
Conclusions:
Sodium and potassium intake estimation was moderately under-
estimated using assays based upon the Horiba twin meter. Compared to standard lab-based methods, the portable device was more practical and convenient.
Measurement of mean population sodium and potassium intake typically
using laboratory -based assays which can add significant logistical burden and costs. A valid field-based measurement method would be a significant advance. In this study, we used 166 24 -hour urine collection samples to compare estimates of sodium, potassium content and sodium/potassium ratio based upon assays done using the field-
based Horiba twin meter versus a laboratory-based method.
Design:
Aliquots of urine were assayed for sodium and potassium using the ion-selective electrode method with the field-based Horiba twin meter and the laboratory-based method. The performance of the Horiba twin meter was determined by comparing field-based estimates of mean
sodium and potassium against those obtained using the laboratory-
based methods.
Setting:
24-hour urine samples were collected as part of an ongoing study being done in rural China.
Subjects:
There were 166 subjects complete 24-hour urine samples available for estimating 24-hour urinary sodium and potassium excretion.
Results:
Mean sodium and potassium excretion were estimated as 170.4 mol/day and 37.4 mmol/day using the meter-based assays and 193.4 mmol/day and 43.8 mmol/day using the laboratory-based assays. There was excellent relative reliability for both sodium (ICC=0.986) and potassium (ICC=0.986). Bland-Altman plots showed moderate-to-good
agreement between two methods.
Conclusions:
Sodium and potassium intake estimation was moderately under-
estimated using assays based upon the Horiba twin meter. Compared to standard lab-based methods, the portable device was more practical and convenient.
Date Issued
2018-01-08
Date Acceptance
2017-11-30
Citation
Public Health Nutrition, 2018, 21 (6), pp.1036-1042
ISSN
1368-9800
Publisher
Cambridge University Press (CUP)
Start Page
1036
End Page
1042
Journal / Book Title
Public Health Nutrition
Volume
21
Issue
6
Copyright Statement
© The Authors 2018. This paper has been accepted for publication and will appear in a revised form, subsequent to peer-review and/or editorial input by Cambridge University Press.
Subjects
Science & Technology
Life Sciences & Biomedicine
Public, Environmental & Occupational Health
Nutrition & Dietetics
Sodium
Potassium
Validation study
Portable device
Urine collection
HIGH BLOOD-PRESSURE
RATIO
EXCRETION
HYPERTENSION
RELIABILITY
ASSOCIATION
AGREEMENT
TRIALS
11 Medical And Health Sciences
Publication Status
Published