The burden of occupationally-related cutaneous malignant melanoma in Britain due to solar radiation
Author(s)
Rushton, L
Hutchings, SJ
Type
Journal Article
Abstract
Background: Increasing evidence highlights the association of occupational exposure and cutaneous malignant melanoma (CMM). We estimated the burden of CMM and total skin cancer burden in Britain due to occupational solar radiation exposure.
Methods: Attributable fractions (AF) and numbers were estimated for CMM mortality and incidence using risk estimates from the published literature and national data sources for proportions exposed. We extended existing methods to account for the exposed population age structure.
Results: The estimated total AF for CMM is 2.0% (95% CI: 1.4–2.7%), giving 48 (95% CI: 33–64) deaths in (2012) and 241 (95% CI: 168–325) registrations (in 2011) attributable to occupational exposure to solar radiation. Higher exposure and larger numbers exposed led to much higher numbers for men than women. Industries of concern are construction, agriculture, public administration and defence, and land transport.
Conclusions: These results emphasise the urgent need to develop appropriate strategies to reduce this burden.
Methods: Attributable fractions (AF) and numbers were estimated for CMM mortality and incidence using risk estimates from the published literature and national data sources for proportions exposed. We extended existing methods to account for the exposed population age structure.
Results: The estimated total AF for CMM is 2.0% (95% CI: 1.4–2.7%), giving 48 (95% CI: 33–64) deaths in (2012) and 241 (95% CI: 168–325) registrations (in 2011) attributable to occupational exposure to solar radiation. Higher exposure and larger numbers exposed led to much higher numbers for men than women. Industries of concern are construction, agriculture, public administration and defence, and land transport.
Conclusions: These results emphasise the urgent need to develop appropriate strategies to reduce this burden.
Date Issued
2017-01-17
Date Acceptance
2016-12-08
Citation
BRITISH JOURNAL OF CANCER, 2017, 116 (4), pp.536-539
ISSN
0007-0920
Publisher
NATURE PUBLISHING GROUP
Start Page
536
End Page
539
Journal / Book Title
BRITISH JOURNAL OF CANCER
Volume
116
Issue
4
Copyright Statement
© 2017 Cancer Research UK. All rights reserved. This manuscript is available under a Creative Commons Attribution Non-Commercial Share Alike License (https://creativecommons.org/licenses/by-nc-sa/2.5/)
Sponsor
The Institution of Occupational Safety & Health
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000394446600015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Grant Number
RC/6100
Subjects
Science & Technology
Life Sciences & Biomedicine
Oncology
occupation
cancer
skin
melanoma
SUN EXPOSURE
CANCER-RISK
SKIN-CANCER
WORKERS
SITE
Oncology & Carcinogenesis
1112 Oncology And Carcinogenesis
Publication Status
Published