A miniature neural recording device to investigate sleep and temperature regulation in mice
File(s)BioCAS2019.pdf (4.83 MB)
Accepted version
Author(s)
Hsieh, Bryan
Harding, Edward
Wisden, William
Franks, Nicholas
Constandinou, Timothy
Type
Conference Paper
Abstract
Sleep is an important and ubiquitous process that,despite decades of research, a large part of its underlyingbiological circuity still remain elusive. To conduct research inthis field, many devices capable of recording neural signalssuch as LFP and EEG have been developed. However, most ofthese devices are unsuitable for sleep studies in mice, the mostcommonly used animals, due to their size and weight. Thus, thispaper presents a novel 4 channel, compact ( 2.1cm by 1.7cm )and lightweight ( 3.6g ) neural-logging device that can recordfor 3 days on just two 0.6g zinc air 312 batteries. Instead ofthe typical solution of using multiple platforms, the presenteddevice integrates high resolution EEG, EMG and temperaturerecordings into one platform. The onboard BLE module allowsthe device to be controlled wirelessly as well as stream data in realtime, enabling researchers to check the progress of the recordingwith minimal animal disturbance. The device demonstrates itsability to accurately record EEG and temperature data throughthe long 24 hour in-vivo recordings conducted. The obtainedEEG data could be easily sleep scored and the temperaturesvalues were all within expected physiological range.
Date Issued
2019-12-05
Date Acceptance
2019-08-12
Citation
2019, pp.1-4
Publisher
IEEE
Start Page
1
End Page
4
Copyright Statement
© 2019 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Sponsor
Engineering & Physical Science Research Council (EPSRC)
Engineering & Physical Science Research Council (E
Wellcome Trust
Identifier
https://ieeexplore.ieee.org/document/8918722
Grant Number
EP/M020975/1
EP/R511547/1
107839/Z/15/Z
Source
IEEE Biomedical Circuits and Systems (BioCAS) Conference
Subjects
Science & Technology
Technology
Computer Science, Information Systems
Engineering, Biomedical
Engineering, Electrical & Electronic
Computer Science
Engineering
Neural recording
neural interface
wireless headstage
implantable device
sleep analysis
research tool
Publication Status
Published
Start Date
2019-10-17
Finish Date
2019-10-19
Coverage Spatial
Nara, Japan
Date Publish Online
2019-12-05