Microfluidic contact lenses for ocular diagnostics and drug delivery
Author(s)
Type
Journal Article
Abstract
The human eye and tear provide essential physiological information for the detection of ocular dysfunctions and therapy monitoring. The measurements of biomarkers in tear composition are critical for disease diagnosis and early interventions. Hence, significant efforts are dedicated to the development of functional contact lenses that can quantify tear analytes and ocular physiological condition. The combination of microfluidics and contact lens technologies offer real-time monitoring of ocular physiology and timely detection of eye disorders through wireless components. This review discusses the fundamentals of microfluidic contact lenses and their diverse applications in ophthalmic diagnostics and drug delivery. It also elucidates the strategies for the commercialization of microfluidic contact lenses to create clinical and point-of-care products.
Date Issued
2023-01-01
Date Acceptance
2022-12-12
Citation
Nano Select, 2023, 4 (1), pp.79-89
ISSN
2688-4011
Publisher
Wiley-VCH
Start Page
79
End Page
89
Journal / Book Title
Nano Select
Volume
4
Issue
1
Copyright Statement
© 2022 The Authors. Nano Select published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
License URL
Identifier
10.1002/nano.202200202
Subjects
biosensors
corneal health
diagnostics
drug delivery
EYE
Materials Science
Materials Science, Multidisciplinary
Nanoscience & Nanotechnology
ocular dysfunction
ophthalmology
RELEASE
Science & Technology
Science & Technology - Other Topics
tear detection
TECHNOLOGIES
Technology
Publication Status
Published
Date Publish Online
2022-12-22