Community-based recruitment of patients with COPD into clinical research
File(s)
Author(s)
Type
Journal Article
Abstract
Identifying subjects for clinical trials is difficult and the evidence base for recruitment strategies is limited, particularly in the field of COPD. We compared the efficiency and patient characteristics of different community-based recruitment strategies during a non-commercial COPD trial in the UK. Recruiting from general practice COPD registers was less efficient and identified patients with significantly milder disease than recruiting through pulmonary rehabilitation and patient groups. We report our experience and propose that pulmonary rehabilitation and patient groups may represent an enriched pool of COPD patients to recruit into clinical trials. TRIAL REGISTRATION NUMBER: EudraCT 2011-001063-43.
Date Issued
2014-09-12
Date Acceptance
2014-02-12
Citation
Thorax, 2014, 69 (10), pp.951-952
ISSN
1468-3296
Publisher
BMJ
Start Page
951
End Page
952
Journal / Book Title
Thorax
Volume
69
Issue
10
Copyright Statement
© 2020 The Author(s). This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/
License URL
Identifier
http://www.ncbi.nlm.nih.gov/pubmed/24595667
Subjects
Science & Technology
Life Sciences & Biomedicine
Respiratory System
COPD Epidemiology
Pulmonary Rehabilitation
Biomedical Research
General Practice
Humans
Patient Selection
Pulmonary Disease, Chronic Obstructive
United Kingdom
Humans
Pulmonary Disease, Chronic Obstructive
Biomedical Research
Patient Selection
General Practice
United Kingdom
1103 Clinical Sciences
Respiratory System
Notes
Brill, Simon E El-Emir, Ethaar Allinson, James P Donaldson, Gavin C Nazareth, Irwin Wedzicha, Jadwiga A Thorax. 2014 Mar 4. doi: 10.1136/thoraxjnl-2014-205253. Identifying subjects for clinical trials is difficult and the evidence base for recruitment strategies is limited, particularly in the field of COPD. We compared the efficiency and patient characteristics of different community-based recruitment strategies during a non-commercial COPD trial in the UK. Recruiting from general practice COPD registers was less efficient and identified patients with significantly milder disease than recruiting through pulmonary rehabilitation and patient groups. We report our experience and propose that pulmonary rehabilitation and patient groups may represent an enriched pool of COPD patients to recruit into clinical trials. TRIAL REGISTRATION NUMBER: EudraCT 2011-001063-43.
Date Publish Online
2014-03-04