Substitutions in the Escherichia coli RNA polymerase inhibitor T7 Gp2 that allow inhibition of transcription when the primary interaction interface between Gp2 and RNA polymerase becomes compromised

Shadrin, A; Sheppard, C; Severinov, K; Matthews, S; Wigneshweraraj, S

doi:https://dx.doi.org/10.1099/mic.0.062547-0

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Substitutions in the Escherichia coli RNA polymerase inhibitor T7 Gp2 that allow inhibition of transcription when the primary interaction interface between Gp2 and RNA polymerase becomes compromised.pdf (1.07 MB)

Published version

Author(s)

Shadrin, A

Sheppard, C

Severinov, K

Matthews, S

Wigneshweraraj, S

Type

Journal Article

Date Issued

2012-11-01

URI

http://hdl.handle.net/10044/1/53576

DOI

https://dx.doi.org/10.1099/mic.0.062547-0

ISSN

1350-0872

Publisher

SOC GENERAL MICROBIOLOGY

Start Page

2753

End Page

2764

Journal / Book Title

MICROBIOLOGY-SGM

Volume

158

Copyright Statement

This is an open access article published by the Microbiology Society under the Creative Commons Attribution License

Sponsor

Biotechnology and Biological Sciences Research Council (BBSRC)

Identifier

http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000312179200008&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202

Grant Number

BB/E023703/1

BB/K000233/1

Subjects

Science & Technology

Life Sciences & Biomedicine

Microbiology

MICROBIOLOGY

DNA

PROTEIN

REPLICATION

INITIATION

Amino Acid Sequence

Amino Acid Substitution

Bacteriophage T7

Binding Sites

DNA-Directed RNA Polymerases

Down-Regulation

Enzyme Inhibitors

Escherichia coli

Escherichia coli Proteins

Molecular Sequence Data

Repressor Proteins

Sequence Alignment

Transcription, Genetic

Viral Proteins

MD Multidisciplinary

Publication Status

Published