Cost – utility analysis of bariatric surgery
File(s)Accepted version.docx (232.02 KB)
Accepted version
Author(s)
Borisenko, Oleg
Lukyanov, Vassily
Ahmed, AR
Type
Journal Article
Abstract
Background:
The objective of the study was to evaluate the cost–utility of bariatric surgery in England.
Methods:
A state-transition Markov model was developed to compare the costs and outcomes of two
treatment approaches for patients with morbid obesity: bariatric surgery, including gastric bypass, sleeve
gastrectomy and adjustable gastric banding; and non-surgical usual care. Parameters of the effectiveness
of surgery and complications were informed by data from the UK National Bariatric Surgery Registry, the
Scandinavian Obesity Registry and the Swedish Obese Subjects study. Costs and utilities were informed
by UK sources.
Results:
Bariatric surgery was associated with reduced mean costs to the health service by €2742 (£1944),
and gain of 0
⋅
8 life-years and 4
⋅
0 quality-adjusted life years (QALYs) over a lifetime compared with usual
care. Bariatric surgery also had the potential to reduce the lifetime risks of obesity-related cardiovascular
diseases and diabetes. Delaying surgery for up to 3 years resulted in a reduction of 0
⋅
7 QALYs and a minor
decrease of €2058 (£1459) in associated healthcare costs.
Conclusion:
Currently used surgical methods were found to be cost saving over the lifetime of individuals
treated in England. Delays in surgical provision can lead to a loss of clinical benefits.
The objective of the study was to evaluate the cost–utility of bariatric surgery in England.
Methods:
A state-transition Markov model was developed to compare the costs and outcomes of two
treatment approaches for patients with morbid obesity: bariatric surgery, including gastric bypass, sleeve
gastrectomy and adjustable gastric banding; and non-surgical usual care. Parameters of the effectiveness
of surgery and complications were informed by data from the UK National Bariatric Surgery Registry, the
Scandinavian Obesity Registry and the Swedish Obese Subjects study. Costs and utilities were informed
by UK sources.
Results:
Bariatric surgery was associated with reduced mean costs to the health service by €2742 (£1944),
and gain of 0
⋅
8 life-years and 4
⋅
0 quality-adjusted life years (QALYs) over a lifetime compared with usual
care. Bariatric surgery also had the potential to reduce the lifetime risks of obesity-related cardiovascular
diseases and diabetes. Delaying surgery for up to 3 years resulted in a reduction of 0
⋅
7 QALYs and a minor
decrease of €2058 (£1459) in associated healthcare costs.
Conclusion:
Currently used surgical methods were found to be cost saving over the lifetime of individuals
treated in England. Delays in surgical provision can lead to a loss of clinical benefits.
Date Issued
2018-09-01
Date Acceptance
2018-02-11
Citation
British Journal of Surgery, 2018, 105 (10), pp.1328-1337
ISSN
1365-2168
Publisher
Wiley
Start Page
1328
End Page
1337
Journal / Book Title
British Journal of Surgery
Volume
105
Issue
10
Copyright Statement
© 2018 BJS Society Ltd Published by John Wiley & Sons Ltd. This is the pre-peer reviewed version of the following article, which has been published in final form at https://onlinelibrary.wiley.com/doi/abs/10.1002/bjs.10857
Subjects
Science & Technology
Life Sciences & Biomedicine
Surgery
BODY-MASS INDEX
BLOOD-PRESSURE
ECONOMIC-EVALUATION
DIABETES-MELLITUS
NATIONAL-HEALTH
LIFE-STYLE
RISK
METAANALYSIS
OBESITY
OUTCOMES
11 Medical And Health Sciences
Publication Status
Published
Date Publish Online
2018-04-17