Detection and tracking volumes of interest in 3D printed tissue engineering scaffolds using 4D imaging modalities.
File(s)
Author(s)
Type
Conference Paper
Abstract
Additive manufacturing (AM) platforms allow the production of patient tissue engineering scaffolds with desirable architectures. Although AM platforms offer exceptional control on architecture, post-processing methods such as sintering and freeze-drying often deform the printed scaffold structure. In-situ 4D imaging can be used to analyze changes that occur during post-processing. Visualization and analysis of changes in selected volumes of interests (VOIs) over time are essential to understand the underlining mechanisms of scaffold deformations. Yet, automated detection and tracking of VOIs in the 3D printed scaffold over time using 4D image data is currently an unsolved image processing task. This paper proposes a new image processing technique to segment, detect and track volumes of interest in 3D printed tissue engineering scaffolds. The method is validated using a 4D synchrotron sourced microCT image data captured during the sintering of bioactive glass scaffolds in-situ. The proposed method will contribute to the development of scaffolds with controllable designs and optimum properties for the development of patient-specific scaffolds.
Date Issued
2021-11
Date Acceptance
2021-07-15
Citation
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2021, pp.1230-1233
ISSN
1557-170X
Start Page
1230
End Page
1233
Journal / Book Title
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
Copyright Statement
© 2021 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Sponsor
National Institute for Health Research
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/34891509
Grant Number
GHR Project: 16/137/45
Source
43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)
Subjects
Humans
Printing, Three-Dimensional
Tissue Engineering
Tissue Scaffolds
X-Ray Microtomography
Publication Status
Published
Start Date
2021-11-01
Finish Date
2021-11-05
Coverage Spatial
Mexico
Date Publish Online
2021-12-09