Restrictive spirometry pattern is associated with low physical activity levels. A population based international study
File(s)
Supporting information
Accepted version
Author(s)
Type
Journal Article
Abstract
Introduction: Restrictive spirometry pattern is an under-recognised disorder with a poor morbidity and mortality prognosis. We compared physical activity levels between adults with a restrictive spirometry pattern and with normal spirometry. Methods: Restrictive spirometry pattern was defined as a having post-bronchodilator FEV1/FVC ≥ Lower Limit of Normal and a FVC<80% predicted in two population-based studies (ECRHS-III and SAPALDIA3). Physical activity was measured using the International Physical Activity Questionnaire. The odds of having low physical activity (<1st study-specific tertile) was evaluated using adjusted logistic regression models. Results: Subjects with a restrictive spirometry pattern (n = 280/4721 in ECRHS, n = 143/3570 in SAPALDIA) reported lower levels of physical activity than those with normal spirometry (median of 1770 vs 2253 MET·min/week in ECRHS, and 3519 vs 3945 MET·min/week in SAPALDIA). Subjects with a restrictive spirometry pattern were more likely to report low physical activity (meta-analysis odds ratio: 1.41 [95%CI 1.07–1.86]) than those with a normal spirometry. Obesity, respiratory symptoms, co-morbidities and previous physical activity levels did not fully explain this finding. Conclusion: Adults with a restrictive spirometry pattern were more likely to report low levels of physical activity than those with normal spirometry. These results highlight the need to identify and act on this understudied but prevalent condition.
Date Issued
2019-01-01
Date Acceptance
2018-11-28
Citation
Respiratory Medicine, 2019, 146, pp.116-123
ISSN
0954-6111
Start Page
116
End Page
123
Journal / Book Title
Respiratory Medicine
Volume
146
Copyright Statement
© 2018 Elsevier Ltd. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence http://creativecommons.org/licenses/by-nc-nd/4.0/
Sponsor
Medical Research Council (MRC)
Commission of the European Communities
Grant Number
G0901214
633212
Subjects
Science & Technology
Life Sciences & Biomedicine
Cardiac & Cardiovascular Systems
Respiratory System
Cardiovascular System & Cardiology
Restrictive spirometry pattern
Body mass index
Epidemiology
Lung function
Physical activity
LUNG-FUNCTION
ACTIVITY QUESTIONNAIRE
NATIONAL-HEALTH
MORTALITY
DISEASE
IMPAIRMENT
DISORDER
EVENTS
RISK
1102 Cardiovascular Medicine And Haematology
1103 Clinical Sciences
Publication Status
Published
Date Publish Online
2018-12-15