How does mild hypothermia affect monoclonal antibody glycosylation?
File(s)Sou et al. Mild Hypothermia_submitted.pdf (2.15 MB)
Accepted version
Author(s)
Type
Journal Article
Date Issued
2015-04-27
Date Acceptance
2014-12-15
Citation
Biotechnology and Bioengineering, 2015, 112 (6), pp.1165-1176
ISSN
1097-0290
Publisher
Wiley
Start Page
1165
End Page
1176
Journal / Book Title
Biotechnology and Bioengineering
Volume
112
Issue
6
Copyright Statement
This is the peer reviewed version of the following article: Sou, S. N., Sellick, C., Lee, K., Mason, A., Kyriakopoulos, S., Polizzi, K. M. and Kontoravdi, C. (2015), How does mild hypothermia affect monoclonal antibody glycosylation?. Biotechnol. Bioeng., 112: 1165–1176. doi: 10.1002/bit.25524, which has been published in final form at http://dx.doi.org/10.1002/bit.25524. This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.
Subjects
Science & Technology
Life Sciences & Biomedicine
Biotechnology & Applied Microbiology
mild hypothermia
cell metabolism
glycosylation
mAb productivity
glycosvltransferase
flux balance analysis
HAMSTER OVARY CELLS
LOW CULTURE TEMPERATURE
MAMMALIAN-CELLS
CHO-CELLS
ERYTHROPOIETIN
PRODUCTIVITY
EXPRESSION
METABOLOMICS
EXTRACTION
PROTEOME
Publication Status
Published