The population genetics of partial diapause, with applications to the aestivating malaria mosquito Anopheles coluzzi
Author(s)
Mwima, Rita
Hui, Tin-Yu J
Kayondo, Jonathan K
Burt, Austin
Type
Journal Article
Abstract
Diapause, a form of dormancy to delay or halt the reproductive development duringunfavourable seasons, has evolved in many insect species. One example is aestivation,an adult-stage diapause enhancing malaria vectors' survival during the dry season (DS)and their re-establishment in the next rainy season (RS). This work develops a novelgenetic approach to estimate the number or proportion of individuals undergoing dia-pause, as well as the breeding sizes of the two seasons, using signals from temporalallele frequency dynamics. Our modelling shows the magnitude of drift is dampenedat early RS when previously aestivating individuals reappear. Aestivation severely bi-ases the temporal effective population size (N e), leading to overestimation of the DSbreeding size by 1 ∕ (1 − 𝛼)2 across 1 year, where 𝛼 is the aestivating proportion. Wefind sampling breeding individuals in three consecutive seasons starting from an RS issufficient for parameter estimation, and perform extensive simulations to verify ourderivations. This method does not require sampling individuals in the dormant state,the biggest challenge in most studies. We illustrate the method by applying it to apublished data set for Anopheles coluzzii mosquitoes from Thierola, Mali. Our methodand the expected evolutionary implications are applicable to any species in which afraction of the population diapauses for more than one generation, and are difficult orimpossible to sample during that stage.
Date Issued
2024-05-01
Date Acceptance
2024-03-08
Citation
Molecular Ecology Resources, 2024, 24 (4)
ISSN
1471-8278
Publisher
Wiley
Journal / Book Title
Molecular Ecology Resources
Volume
24
Issue
4
Copyright Statement
© 2024 The Authors. Molecular Ecology Resources published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
License URL
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/38511493
Subjects
aestivation
Biochemistry & Molecular Biology
diapause
DRY SEASON
Ecology
Environmental Sciences & Ecology
Evolutionary Biology
GAMBIAE
genetic drift
Life Sciences & Biomedicine
persistence
Science & Technology
SIZE
temporal allele frequency
Publication Status
Published
Coverage Spatial
England
Article Number
e13949
Date Publish Online
2024-03-21