Modelling the impact of an HIV testing intervention on HIV transmission among men who have sex with men in China
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Supporting information
Published version
Author(s)
Type
Journal Article
Abstract
Objectives
An intervention developed through participatory crowdsourcing methods increased HIV self‐testing among men who have sex with men [MSM; relative risk (RR) = 1.89]. We estimated the long‐term impact of this intervention on HIV transmission among MSM in four cities (Guangzhou, Shenzhen, Jinan and Qingdao).
Methods
A mathematical model of HIV transmission, testing and treatment among MSM in China was parameterized using city‐level demographic and sexual behaviour data and calibrated to HIV prevalence, diagnosis and antiretroviral therapy (ART) coverage data. The model was used to project the HIV infections averted over 20 years (2016–2036) from the intervention to increase self‐testing, compared with current testing rates.
Results
Running the intervention once would avert < 2.2% infections over 20 years. Repeating the intervention (RR = 1.89) annually would avert 6.4–10.7% of new infections, while further increases in the self‐testing rate (hypothetical RR = 3) would avert 11.7–20.7% of new infections.
Conclusions
Repeated annual interventions would give a three‐ to seven‐fold increase in long‐term impact compared with a one‐off intervention. Other interventions will be needed to more effectively reduce the HIV burden in this population.
An intervention developed through participatory crowdsourcing methods increased HIV self‐testing among men who have sex with men [MSM; relative risk (RR) = 1.89]. We estimated the long‐term impact of this intervention on HIV transmission among MSM in four cities (Guangzhou, Shenzhen, Jinan and Qingdao).
Methods
A mathematical model of HIV transmission, testing and treatment among MSM in China was parameterized using city‐level demographic and sexual behaviour data and calibrated to HIV prevalence, diagnosis and antiretroviral therapy (ART) coverage data. The model was used to project the HIV infections averted over 20 years (2016–2036) from the intervention to increase self‐testing, compared with current testing rates.
Results
Running the intervention once would avert < 2.2% infections over 20 years. Repeating the intervention (RR = 1.89) annually would avert 6.4–10.7% of new infections, while further increases in the self‐testing rate (hypothetical RR = 3) would avert 11.7–20.7% of new infections.
Conclusions
Repeated annual interventions would give a three‐ to seven‐fold increase in long‐term impact compared with a one‐off intervention. Other interventions will be needed to more effectively reduce the HIV burden in this population.
Date Issued
2021-07-01
Date Acceptance
2020-12-14
Citation
HIV Medicine, 2021, 22 (6), pp.467-477
ISSN
1464-2662
Publisher
Wiley
Start Page
467
End Page
477
Journal / Book Title
HIV Medicine
Volume
22
Issue
6
Copyright Statement
© 2021 The Authors. HIV Medicine published by John Wiley & Sons Ltd on behalf of British HIV Association
This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Sponsor
National Institutes of Health
Grant Number
5108768
Subjects
Science & Technology
Life Sciences & Biomedicine
Infectious Diseases
crowdsourcing
HIV
MSM
self-testing intervention
HIV
MSM
crowdsourcing
self-testing intervention
Virology
1103 Clinical Sciences
Publication Status
Published
Date Publish Online
2021-01-28