Late gadolinium enhancement imaging and sudden cardiac death
File(s)
Published version
Author(s)
Type
Journal Article
Abstract
The prediction and management of sudden cardiac death risk continue to pose significant challenges in cardiovascular care despite advances in therapies over the last two decades. Late gadolinium enhancement (LGE) on cardiac magnetic resonance—a marker of myocardial fibrosis—is a powerful non-invasive tool with the potential to aid the prediction of sudden death and direct the use of preventative therapies in several cardiovascular conditions. In this state-of-the-art review, we provide a critical appraisal of the current evidence base underpinning the utility of LGE in both ischaemic and non-ischaemic cardiomyopathies together with a focus on future perspectives and the role for machine learning and digital twin technologies.
Date Issued
2025-09-21
Date Acceptance
2025-06-16
Citation
European Heart Journal, 2025, 46 (36), pp.3555-3568
ISSN
0195-668X
Publisher
Oxford University Press
Start Page
3555
End Page
3568
Journal / Book Title
European Heart Journal
Volume
46
Issue
36
Copyright Statement
© The Author(s) 2025. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
License URL
Identifier
10.1093/eurheartj/ehaf464
Subjects
Sudden cardiac death
Late gadolinium enhancement
Cardiac magnetic resonance
Cardiomyopathy
Outcomes
Publication Status
Published
Article Number
ehaf464
Date Publish Online
2025-07-16