Adjuncts for sputum clearance in COPD – clinical consensus vs actual use
File(s)Acapella BMJ open resp V2 clean.docx (48.8 KB)
Accepted version
Author(s)
Barker, R
Laverty, A
Hopkinson, NS
Type
Journal Article
Abstract
Introduction Oscillatory positive pressure devices can be used as adjuncts to improve sputum clearance in COPD, though the evidence base is incomplete. The attitudes of physiotherapists towards the place of these devices in the care of COPD patients is not known. In addition, their actual use in practice compared to the prescription of medications has not been studied.
Methods We analysed English prescribing data, obtained from OpenPrescribing.net, for a three year period from 2013. In addition we conducted an online survey of members of the Association of Chartered Physiotherapists in Respiratory Care (ACPRC) asking about awareness of devices, thresholds for treatment and device preference.
Results Out of a potential 3.2 million COPD patient years of treatment between 2013-2015, 422,744 patient years of treatment with carbocisteine, at a cost of £73 million were prescribed, as well as 1.1 million years treatment with tiotropium. In the same period only 4,989 OPEP devices were prescribed. Given overlapping indications for OPEP devices and carbocisteine this disparity requires explanation. There were 116 responses to the survey (12% response rate), 72% in hospital practice, 28% based in the community. There were variations in respondents’ threshold for treatment with sputum adjuncts in COPD. Asked to choose between the Acapella®, Flutter® and Positive Expiratory Pressure mask (PEP), if only one were available, preferences were 69%, 24% and 6% respectively.
Conclusions There is a one-hundred fold difference between use of carbocisteine and OPEP devices in COPD, with far fewer devices being prescribed than are included in the phenotypes that clinicians believe they are effective in. Variation in physiotherapist attitudes to treatment thresholds highlights the need for research into the effectiveness of OPEP devise in specific patient phenotypes.
Methods We analysed English prescribing data, obtained from OpenPrescribing.net, for a three year period from 2013. In addition we conducted an online survey of members of the Association of Chartered Physiotherapists in Respiratory Care (ACPRC) asking about awareness of devices, thresholds for treatment and device preference.
Results Out of a potential 3.2 million COPD patient years of treatment between 2013-2015, 422,744 patient years of treatment with carbocisteine, at a cost of £73 million were prescribed, as well as 1.1 million years treatment with tiotropium. In the same period only 4,989 OPEP devices were prescribed. Given overlapping indications for OPEP devices and carbocisteine this disparity requires explanation. There were 116 responses to the survey (12% response rate), 72% in hospital practice, 28% based in the community. There were variations in respondents’ threshold for treatment with sputum adjuncts in COPD. Asked to choose between the Acapella®, Flutter® and Positive Expiratory Pressure mask (PEP), if only one were available, preferences were 69%, 24% and 6% respectively.
Conclusions There is a one-hundred fold difference between use of carbocisteine and OPEP devices in COPD, with far fewer devices being prescribed than are included in the phenotypes that clinicians believe they are effective in. Variation in physiotherapist attitudes to treatment thresholds highlights the need for research into the effectiveness of OPEP devise in specific patient phenotypes.
Date Issued
2017-07-01
Date Acceptance
2017-06-20
Citation
BMJ Open Respiratory Research, 2017, 4
ISSN
2052-4439
Publisher
BMJ Publishing Group
Journal / Book Title
BMJ Open Respiratory Research
Volume
4
Copyright Statement
© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Publication Status
Published
Article Number
e000226