Mucormycosis (zygomycosis) of renal allograft
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Author(s)
Gupta, Krishan L
Joshi, Kusum
Kohli, Harbir S
Jha, Vivekanand
Sakhuja, Vinay
Type
Journal Article
Abstract
Fungal infection is relatively common among renal transplant recipients from developing countries. Mucormycosis, also known as zygomycosis, is one of the most serious fungal infections in these patients. The most common of presentation is rhino-cerebral. Isolated involvement of a renal allograft is very rare. A thorough search of literature and our medical records yielded a total of 24 cases with mucormycosis of the transplanted kidney. There was an association with cytomegalovirus (CMV) infection and anti-rejection treatment in these patients and most of these transplants were performed in the developing countries from unrelated donors. The outcome was very poor with an early mortality in 13 (54.5%) patients. Renal allograft mucormycosis is a relatively rare and potentially fatal complication following renal transplantation. Early diagnosis, graft nephrectomy and appropriate antifungal therapy may result in an improved prognosis for these patients.
Date Issued
2012-12-01
Date Acceptance
2012-08-18
Citation
Clinical Kidney Journal, 2012, 5 (6), pp.502-507
ISSN
2048-8505
Publisher
European Renal Association - European Dialysis and Transplant Association (ERA-EDTA)
Start Page
502
End Page
507
Journal / Book Title
Clinical Kidney Journal
Volume
5
Issue
6
Copyright Statement
© The Author 2012. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For permissions, please email: journals.permissions@oup.com.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
License URL
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/26069793
PII: sfs130
Subjects
cytomegalovirus infection
immunosuppression
mucormycosis
renal allograft
Publication Status
Published
Coverage Spatial
England
Date Publish Online
2012-11-08