Iterative synthesis of oligo[n]rotaxanes in excellent yield
Author(s)
Lewis, James EM
Winn, Joby
Cera, Luca
Goldup, Stephen M
Type
Journal Article
Abstract
We present an operationally simple iterative coupling strategy for the synthesis of oligomeric homo- and hetero[n]rotaxanes with precise control over the position of each macrocycle. The exceptional yield of the AT-CuAAC reaction, combined with optimized conditions that allow the rapid synthesis of the target oligomers, opens the door to the study of precision-engineered oligomeric interlocked molecules.
Date Issued
2016-12-21
Date Acceptance
2016-10-01
Citation
Journal of the American Chemical Society, 2016, 138 (50), pp.16329-16336
ISSN
1520-5126
Publisher
American Chemical Society
Start Page
16329
End Page
16336
Journal / Book Title
Journal of the American Chemical Society
Volume
138
Issue
50
Copyright Statement
© 2016 American Chemical Society. This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of the American Chemical Society, after peer review and technical editing by the publisher. To access the final edited and published work see https://dx.doi.org/10.1021/jacs.6b08958
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000390729500027&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
Science & Technology
Physical Sciences
Chemistry, Multidisciplinary
Chemistry
ACTIVE-TEMPLATE SYNTHESIS
INSULATED MOLECULAR WIRES
AZIDE-ALKYNE CYCLOADDITION
OXIDE) TRIBLOCK COPOLYMERS
BLOCK-SELECTED INCLUSION
ANION-BINDING CATALYSIS
CLICK CHEMISTRY
SOLID-PHASE
HOST-GUEST
ALPHA-CYCLODEXTRIN
Publication Status
Published
Date Publish Online
2016-10-18