Saltatory waves in the spike-diffuse-spike model of active dendritic spines
File(s)
Published version
Author(s)
Coombes, S
Bressloff, PC
Type
Journal Article
Abstract
In this Letter we present the explicit construction of a saltatory traveling pulse of nonconstant profile in an idealized model of dendritic tissue. Excitable dendritic spine clusters, modeled with integrate-and-fire (IF) units, are connected to a passive dendritic cable at a discrete set of points. The saltatory nature of the wave is directly attributed to the breaking of translation symmetry in the cable. The conditions for propagation failure are presented as a function of cluster separation and IF threshold.
Date Issued
2003-07-11
Date Acceptance
2003-07-01
Citation
Physical Review Letters, 2003, 91 (2)
ISSN
0031-9007
Publisher
American Physical Society
Journal / Book Title
Physical Review Letters
Volume
91
Issue
2
Copyright Statement
©2003 American Physical Society
Identifier
http://dx.doi.org/10.1103/physrevlett.91.028102
Publication Status
Published
Article Number
028102
Date Publish Online
2003-07-09