Copper catalysed oxidative α-sulfonylation of branched aldehydes using the acid enhanced reactivity of manganese(IV) oxide
File(s)MS Sulfonyl aldehydes revised submit.pdf (574.46 KB)
Accepted version
Author(s)
Higham, J
Bull, James A
Type
Journal Article
Abstract
The oxidative coupling of secondary aldehydes and sulfinate salts is achieved using copper catalysis to form a-sulfonyl aldehydes. The use of an acidic co-solvent is important to adjust the oxidation potential of MnO2 as oxidant. A broad range of sulfonylated aldehydes is prepared, and their further functionalisation is demonstrated. A dual ionic/radical pathway mechanism is proposed.
Date Issued
2020-03-17
Date Acceptance
2020-03-17
Citation
Chemical Communications, 2020, 56 (33), pp.4587-4590
ISSN
1359-7345
Publisher
Royal Society of Chemistry (RSC)
Start Page
4587
End Page
4590
Journal / Book Title
Chemical Communications
Volume
56
Issue
33
Copyright Statement
© The Royal Society of Chemistry 2020.
Sponsor
The Royal Society
The Royal Society
The Royal Society
Identifier
https://pubs.rsc.org/en/content/articlelanding/2020/cc/d0cc01576h#!divAbstract
Grant Number
UF140161
RG150444
RGF\EA\180031
Subjects
Organic Chemistry
03 Chemical Sciences
Publication Status
Published online
Date Publish Online
2020-03-17