Tumour necrosis factor-alpha regulates human rosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-kappa B and AP-1

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Author(s)

Kankaanranta, H

Ilmarinen, P

Zhang, X

Adcock, IM

Lahti, A

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Type

Journal Article

Date Issued

2014-02-28

Date Acceptance

2014-02-02

Citation

PLOS One, 2014, 9 (2)

URI

http://hdl.handle.net/10044/1/31703

DOI

https://www.dx.doi.org/10.1371/journal.pone.0090298

ISSN

1932-6203

Publisher

Public Library of Science

Journal / Book Title

PLOS One

Volume

9

Issue

2

Copyright Statement

© 2014 Kankaanranta et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

License URL

http://creativecommons.org/licenses/by/4.0/

Sponsor

Medical Research Council (MRC)

Grant Number

G1000758

Subjects

Science & Technology

Multidisciplinary Sciences

Science & Technology - Other Topics

MULTIDISCIPLINARY SCIENCES

IN-VITRO

CELL LIFE

C-JUN

ACTIVATION

ASTHMA

INHIBITION

SURVIVAL

KINASE

DEATH

JNK

Antibodies

Antigens, CD95

Apoptosis

Asthma

Cell Survival

Eosinophils

Gene Expression Regulation

Gliotoxin

Humans

I-kappa B Kinase

Imidazoles

NF-kappa B

Phosphorylation

Primary Cell Culture

Protein Binding

Pyrrolidines

Quinoxalines

Receptors, Tumor Necrosis Factor, Type I

Retinoids

Signal Transduction

Thiocarbamates

Transcription Factor AP-1

Tumor Necrosis Factor-alpha

General Science & Technology

MD Multidisciplinary

Publication Status

Published

Article Number

e90298