The impact of e-cigarette exposure on different organ systems: a review of recent evidence and future perspectives
File(s)
Published version
Author(s)
Ali, Nurshad
Xavier, Joseph
Engur, Melih
Mohanan, P
de la Serna, Jorge Bernardino
Type
Journal Article
Abstract
The use of electronic cigarettes (e-cigs) is rapidly increasing worldwide and is promoted as a smoking cessation tool. The impact of traditional cigs on human health has been well-defined in both animal and human studies. In contrast, little is known about the adverse effects of e-cigs exposure on human health. This review summarizes the impact of e-cigs exposure on different organ systems based on the rapidly expanding recent evidence from experimental and human studies. A number of growing studies have shown the adverse effects of e-cigs exposure on various organ systems. The summarized data in this review indicate that while e-cigs use causes less adverse effects on different organs compared to traditional cigs, its long-term exposure may lead to serious health effects. Data on short-term organ effects are limited and there is no sufficient evidence on long-term organ effects. Moreover, the adverse effects of secondhand and third hand e-cigs vapour exposure have not been thoroughly investigated in previous studies. Although some studies demonstrated e-cigs used as a smoking cessation tool, there is a lack of strong evidence to support it. While some researchers suggested e-cigs as a safer alternative to tobacco smoking, their long-term exposure health effects remain largely unknown. Therefore, more epidemiological and prospective studies including mechanistic studies are needed to address the potential adverse health effects of e-cigs to draw a firm conclusion about their safe use. A wide variation in e-cigs products and the lack of standardized testing methods are the major barriers to evaluating the existing data. Specific regulatory guidelines for both e-cigs components and the manufacturing process may be effective to protect consumer health.
Date Issued
2023-09-05
Date Acceptance
2023-06-08
Citation
Journal of Hazardous Materials, 2023, 457
ISSN
0304-3894
Publisher
Elsevier
Journal / Book Title
Journal of Hazardous Materials
Volume
457
Copyright Statement
© 2023 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
License URL
Identifier
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:001027213700001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
Subjects
AEROSOL EXPOSURE
ELECTRONIC CIGARETTE
Electronic cigarettes
Engineering
Engineering, Environmental
Environmental Sciences
Environmental Sciences & Ecology
Exposure
Health effects
HISTOLOGICAL-CHANGES
HYDROPHILIC POLYMERS
Life Sciences & Biomedicine
NATIVE PULMONARY SURFACTANT
NICOTINE DELIVERY-SYSTEMS
Organ system
OXIDATIVE STRESS
REFILL LIQUID EXPOSURE
Science & Technology
SMOKING-CESSATION
Technology
TOBACCO-SMOKE
Publication Status
Published
Article Number
131828
Date Publish Online
2023-06-12