Characterising spatiotemporal dynamics of arboviruses: mapping risk and assessing the impact of meteorological and environmental conditions on transmission
File(s)
Author(s)
Cox, Victoria
Type
Thesis
Abstract
Arboviruses cause drastic health and economic burdens and are a leading cause of death and disability globally. There is an urgent need to better understand arbovirus transmission drivers to inform surveillance and control of disease. This thesis explores the associations between arbovirus risk and meteorology and environment, and assesses how well these drivers can reconstruct the transmission dynamics of different arboviruses across a range of settings. Furthermore, local hotspots of arbovirus risk are identified and annual patterns in transmission intensity are characterised to explore substantial spatiotemporal heterogeneities in arbovirus transmission patterns. The results of this thesis highlight the health impact of extreme meteorological conditions on local arbovirus transmission, which has important implications for epidemiological modelling and climate planning.
Version
Open Access
Date Issued
2024-05-13
Date Awarded
01/02/2025
License URL
Advisor
Dorigatti, Ilaria
Bhatt, Samir
Faria, Nuno
Sponsor
Wellcome Trust (London, England)
Grant Number
222375/Z/21/Z
Publisher Department
School of Public Health
Publisher Institution
Imperial College London
Qualification Level
Doctoral
Qualification Name
Doctor of Philosophy (PhD)