A CMOS-Based Lab-on-Chip Array for Combined Magnetic Manipulation and Opto-Chemical Sensing
File(s)iscasT2P.pdf (1.6 MB)
Accepted version
Author(s)
Goh, ZDC
Georgiou, P
Constandinou, TG
Prodromakis, T
Toumazou, C
Type
Conference Paper
Abstract
This paper presents a CMOS-based lab-on-chip platform for combined magnetic manipulation and opto-chemical sensing. Within each pixel, a Programmable Gate (PG) ISFET chemical sensor is combined with an active pixel sensor, and is encompassed within an inductive coil. The integrated pixel is tesselated to form an 8×8 array. Fabricated in a commercially available 0.35um CMOS technology, the system can be used for simultaneous optical imaging and pH sensing, and includes auto- calibration mechanisms for eliminating sensor non-idealities. A spatiotemporal magnetic field pattern generator has also been embedded for micro-scale magnetic manipulation. Controlled via a MATLAB based graphical user interface, the system achieves real time data acquisition at 6fps, a pH sensitivity of 57mV/pH and demonstrates magnetic manipulation of micro-beads.
Version
Accepted version
Date Issued
2011
Citation
2011, pp.1997-2001
Publisher
IEEE
Source Title
IEEE International Symposium on Circuits and Systems (ISCAS)
Start Page
1997
End Page
2001
Copyright Statement
© 2011 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Source
IEEE International Symposium on Circuits and Systems (ISCAS)
Source Place
Rio De Janeiro, Brazil
Publication Status
Published
Start Date
2011-05-15
Finish Date
2011-05-18
Coverage Spatial
Rio De Janeiro, Brazil