Contribution of the antibiotic chloramphenicol and its analogues as precursors of dichloroacetamide and other disinfection byproducts in drinking water
File(s)
Accepted version
Author(s)
Chu, W
Krasner, S
Gao, N
Templeton, MR
Yin, D
Type
Journal Article
Abstract
Dichloroacetamide (DCAcAm), a disinfection byproduct, has been detected in drinking water. Previous research showed that amino acids may be DCAcAm precursors. However, other precursors may be present. This study explored the contribution of the antibiotic chloramphenicol (CAP) and two of its analogues (thiamphenicol, TAP; florfenicol, FF) (referred to collectively as CAPs), which occur in wastewater-impacted source waters, to the formation of DCAcAm. Their formation yields were compared to free and combined amino acids, and they were investigated in filtered waters from drinking-water-treatment plants, heavily wastewater-impacted natural waters, and secondary effluents from wastewater treatment plants. CAPs had greater DCAcAm formation potential than two representative amino acid precursors. However, in drinking waters with ng/L levels of CAPs, they will not contribute as much to DCAcAm formation as the μg/L levels of amino acids. Also, the effect of advanced oxidation processes (AOPs) on DCAcAm formation from CAPs in real water samples during subsequent chlorination was evaluated. Preoxidation of CAPs with AOPs reduced the formation of DCAcAm during postchlorination. The results of this study suggest that CAPs should be considered as possible precursors of DCAcAm, especially in heavily wastewater-impacted waters.
Date Issued
2016-01-05
Date Acceptance
2015-12-04
Citation
Environmental Science and Technology, 2016, 50 (1), pp.388-396
ISSN
0013-936X
Publisher
American Chemical Society
Start Page
388
End Page
396
Journal / Book Title
Environmental Science and Technology
Volume
50
Issue
1
Copyright Statement
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Environmental Science and Technology, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://dx.doi.org/10.1021/acs.est.5b04856
Identifier
https://pubs.acs.org/doi/10.1021/acs.est.5b04856
Subjects
Science & Technology
Technology
Life Sciences & Biomedicine
Engineering, Environmental
Environmental Sciences
Engineering
Environmental Sciences & Ecology
NATURAL ORGANIC-MATTER
N-DBPS
MASS-SPECTROMETRY
NITROGEN ORIGINS
EMERGING CLASS
HALOACETAMIDES
TOXICITY
CHLORINATION
RIVER
DICHLOROACETONITRILE
Acetamides
Chloramphenicol
Disinfection
Drinking Water
Halogenation
Waste Water
Water Pollutants
Water Purification
Chloramphenicol
Acetamides
Water Pollutants
Disinfection
Water Purification
Halogenation
Drinking Water
Waste Water
Environmental Sciences
Publication Status
Published
Date Publish Online
2015-12-17