A scoping review of interventions to address TB associated respiratory disability
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Author(s)
Type
Journal Article
Abstract
There is a growing body of data describing a high burden of respiratory morbidity amongst pulmonary TB patients and survivors, with up to half thought to experience residual respiratory symptoms, abnormal spirometry, or structural pathology after TB treatment completion. Many patients experiencing marked impacts on their lives and livelihoods. However, there remain no guidelines or evidence-based frameworks for integrated TB-respiratory care during or post TB treatment completion. In this scoping review, completed in collaboration with the WHO Global Tuberculosis Programme, we have identified a lack of primary data on the clinical efficacy, cost effectiveness or feasibility of six potential interventions for the prevention and management of TB-associated respiratory impairment and disability, with a lack of studies in children and adolescents. There is a need for robust interventional trials to improve the long-term respiratory outcomes of people affected by pulmonary TB disease, and to explore how these might be implemented within resource-limited settings.
Date Issued
2024-07
Date Acceptance
2024-04-30
Citation
EClinicalMedicine, 2024, 73
ISSN
2589-5370
Publisher
Elsevier
Journal / Book Title
EClinicalMedicine
Volume
73
Copyright Statement
© 2024 World Health Organization; licensee Elsevier Ltd. This is an open access article under the CC BY
IGO license (http://creativecommons.org/licenses/by/3.0/igo/).
IGO license (http://creativecommons.org/licenses/by/3.0/igo/).
License URL
Identifier
https://www.sciencedirect.com/science/article/pii/S2589537024002256
Article Number
102646
Date Publish Online
2024-05-27