BACKGROUND & AIMS: The United Kingdom (UK) nutrition database monitors the changing landscape of adult home parenteral nutrition support (HPS) to inform clinicians and policy makers of the need for this life saving treatment. METHODS: The UK database is administered by the British Association for Parenteral and Enteral Nutrition (BAPEN). Data for home parenteral nutrition (HPN) has been collected since 2005 and home intravenous fluids (HIVF) since 2011. During this study the reporting of data to the database by healthcare workers has been voluntary. Data were analysed using linear regression. RESULTS: A 3-fold increase of new registrations for HPS patients was noted on this 10-year period, with notable increase in the numbers of patients with advanced malignancy supported with HPS. Crohn's disease and short bowel syndrome were the leading causes for both HPN and HIVF in the UK. A statistically significant increase in older (p<0.001) and less independent patients using HPS was noted. CONCLUSIONS: The prevalence of HPS is steadily increasing in size with broadening of acceptable performance status. The launch of the Intestinal Failure Registry and mandatory registration will increase accuracy in data reporting. This article is protected by copyright. All rights reserved.