Small lesion classification in dynamic contrast enhancement MRI for breast cancer early detection
File(s)breastcancer.pdf (700.36 KB)
Accepted version
Author(s)
Type
Conference Paper
Abstract
Classification of small lesions is of great importance for early detection of breast cancer. The small size of lesion makes handcrafted features ineffective for practical applications. Furthermore, the relatively small data sets also impose challenges on deep learning based classification methods. Dynamic Contrast Enhancement MRI (DCE-MRI) is widely-used for women at high risk of breast cancer, and the dynamic features become more important in the case of small lesion. To extract more dynamic information, we propose a method for processing sequence data to encode the DCE-MRI, and design a new structure, dense convolutional LSTM, by adding a dense block in convolutional LSTM unit. Faced with the huge number of parameters in deep neural network, we add some semantic priors as constrains to improve generalization performance. Four latent attributes are extracted from diagnostic reports and pathological results, and are predicted together with the classification of benign or malignant. Predicting the latent attributes as auxiliary tasks can help the training of deep neural network, which makes it possible to train complex network with small size dataset and achieve a satisfactory result. Our methods improve the accuracy from 0.625, acquired by ResNet, to 0.847.
Date Issued
2018-09-26
Date Acceptance
2018-09-16
Citation
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), 2018, 11071 LNCS, pp.876-884
ISBN
9783030009335
ISSN
0302-9743
Publisher
Springer Nature Switzerland AG
Start Page
876
End Page
884
Journal / Book Title
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume
11071 LNCS
Copyright Statement
© 2018 Springer Nature Switzerland AG. The final publication is available at Springer via https://dx.doi.org/10.1007/978-3-030-00934-2_97
Source
Medical Image Computing and Computer Assisted Intervention – MICCAI 2018
Subjects
08 Information And Computing Sciences
Artificial Intelligence & Image Processing
Publication Status
Published
Start Date
2018-09-16
Finish Date
2018-09-20
Coverage Spatial
Granada, Spain
Date Publish Online
2018-09-26