Prevalence of Chronic airflow limitation in Kashmir, North India: Results from the BOLD study.
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Published version
Accepted version
Author(s)
Type
Journal Article
Abstract
BACKGROUND: Data on spirometrically defined chronic airflow limitation (CAL) are scarce in developing countries.
OBJECTIVE: To estimate the prevalence of spirometrically defined CAL in Kashmir, North India.
METHODS: Using Burden of Obstructive Lung Disease survey methods, we administered questionnaires to randomly selected adults aged 40 years. Post-bronchodilator spirometry was performed to estimate the prevalence of CAL and its relation to potential risk factors.
RESULTS: Of 1100 participants initially recruited, 953 (86.9%) responded and 757 completed acceptable spirometry and questionnaires. The prevalence of a forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio less than the lower limit of normal was 17.3% (4.5) in males and 14.8% (2.1) in females. Risk factors for CAL included higher age, cooking with wood and lower educational status. The prevalence of current smoking was 61% in males and 22% in females; most smoked hookahs. CAL was found equally in non-smoking males and females, and was independently associated with the use of the hookah, family history of respiratory disease and poor education. A self-reported doctor's diagnosis of chronic obstructive pulmonary disease was reported in 8.4/1000 (0.9% of females and 0.8% of males).
CONCLUSION: Spirometrically confirmed CAL is highly prevalent in Indian Kashmir, and seems to be related to the high prevalence of smoking, predominantly in the form of hookah smoking.
OBJECTIVE: To estimate the prevalence of spirometrically defined CAL in Kashmir, North India.
METHODS: Using Burden of Obstructive Lung Disease survey methods, we administered questionnaires to randomly selected adults aged 40 years. Post-bronchodilator spirometry was performed to estimate the prevalence of CAL and its relation to potential risk factors.
RESULTS: Of 1100 participants initially recruited, 953 (86.9%) responded and 757 completed acceptable spirometry and questionnaires. The prevalence of a forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio less than the lower limit of normal was 17.3% (4.5) in males and 14.8% (2.1) in females. Risk factors for CAL included higher age, cooking with wood and lower educational status. The prevalence of current smoking was 61% in males and 22% in females; most smoked hookahs. CAL was found equally in non-smoking males and females, and was independently associated with the use of the hookah, family history of respiratory disease and poor education. A self-reported doctor's diagnosis of chronic obstructive pulmonary disease was reported in 8.4/1000 (0.9% of females and 0.8% of males).
CONCLUSION: Spirometrically confirmed CAL is highly prevalent in Indian Kashmir, and seems to be related to the high prevalence of smoking, predominantly in the form of hookah smoking.
Date Issued
2016-10-01
Date Acceptance
2016-05-31
Citation
International Journal of Tuberculosis and Lung Disease, 2016, 20 (10), pp.1399-1404
ISSN
1815-7920
Publisher
International Union Against Tuberculosis and Lung Disease
Start Page
1399
End Page
1404
Journal / Book Title
International Journal of Tuberculosis and Lung Disease
Volume
20
Issue
10
Copyright Statement
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted
use, distribution, and reproduction in any medium, provided the
original author and source are credited.
Creative Commons Attribution License, which permits unrestricted
use, distribution, and reproduction in any medium, provided the
original author and source are credited.
License URL
Sponsor
Wellcome Trust
Grant Number
085790/Z/08/Z
Subjects
Microbiology
1102 Cardiovascular Medicine And Haematology
Publication Status
Published